候選原料選定後的配方最佳化
藥物開發是個漫長而複雜的過程,從探索開始,一直到讓政府批准上市才算成功。如下所述,藥物開發過程中的每個步驟都有特定的目標,旨在篩選出適合的活性化合物和候選原料,最終得到已核准的原料藥。
藥物開發是個漫長而複雜的過程,從探索開始,一直到讓政府批准上市才算成功。如下所述,藥物開發過程中的每個步驟都有特定的目標,旨在篩選出適合的活性化合物和候選原料,最終得到已核准的原料藥。
The RS-DSC is for preclinical development of antibodies, antibody-drug conjugates, and vaccines where dosage forms are typically greater than 50 µg.
Printed circuit boards (PCBs) form the backbone of virtually all electronic applications. Enhancing their performance and reliability is paramount for custom PCB projects, where smaller footprints and improved maintainability lead to enhanced functionality.
The most popular tool used to characterize binding in the late-discovery phase of drug development is isothermal titration calorimetry (ITC). ITC is a high-resolution method for complete characterization of the basic chemical details of a binding interaction. The calorimeters accomplish this by measuring the heat that is released or absorbed when molecules interact with each other.
Drug development is a long and complex process that starts with discovery and, if successful, ends with government approval for marketing. Each step in the drug development process, outlined below, has specific goals with the aim of down-selecting appropriate hits and candidates to an approved drug substance.
在整個 18 世紀,許多科學家都對熱的本質提出了質疑。艾薩克·牛頓 (Isaac Newton) 認為熱能是透過粒子的震動傳遞的,而勞勃·虎克 (Robert Hooke) 則認為熱能是人體各部位運動而產生的一種特性1。然而,在歷史上第一個眾所周知對熱量進行測量的貢獻者是蘇格蘭醫生和化學家約瑟夫·布拉克 (Joseph Black)1。1761 年,他透過精確的測量發現,對達熔點的冰或達沸點的水施加熱量並不會導致溫度變化1。這個觀察結果使他成為第一個區分溫度和熱量的科學家,標誌了熱力學的開端。
Overview In this Tech Tip, we will show you how to add …
We expect a lot from our composites: rocket materials need to endure the heat of takeoff, wind turbines must withstand high wind gusts, and sneakers are expected to be durable and supportive on long runs. How do experts develop composites tailored to such specific uses and verify their properties?
從輕薄的筆記型電腦到長途電動汽車,無數應用都需要提高鋰電池的能量密度和性能。由於電池電極直接影響電池的能量密度和性能,因此電池研究人員對電極及其組成特別感興趣,希望將技術推向更高境界。電池漿料加工處理也是製程中的關鍵步驟,是提升效率並降低成本的重大機會。
Rheology for Topical and Personal Care Formulations