TA Instruments Rapid Screening Differential Scanning Calorimeter Product Video
The RS-DSC is for preclinical development of antibodies, antibody-drug conjugates, and vaccines where dosage forms are typically greater than 50 µg.
An Overview of Isothermal Microcalorimetry in Battery R&D and QA
Additional Resources For further information, please see the corresponding app note, An Overview of Isothermal Microcalorimetry in Battery R&D and QA.
Optimizing Formulations After Candidate Selection
Candidate selection is the third phase of the drug development process. The main purpose of candidate selection is to continue screening and filtering down to the most promising antibodies, ideally having one or two progress forward. During this phase, researchers are looking to evaluate the developability of a pool of less than five antibodies.
Applying Dynamic Mechanical Analysis (DMA) to Test the Durability of Protective Sports Equipment
There is a renewed interest in the durability of protective sports equipment after Patrick Mahomes’ helmet recently cracked apart in -4 degrees Fahrenheit (-20 degrees Celsius) weather. Scientists from TA Instruments ran tests to find out if materials found in protective sports equipment can break due to cold weather.
Thermal Analysis for Printed Circuit Boards (PCBs)
Printed circuit boards (PCBs) form the backbone of virtually all electronic applications. Enhancing their performance and reliability is paramount for custom PCB projects, where smaller footprints and improved maintainability lead to enhanced functionality.
TA Instruments RS-DSC
The TA RS-DSC is a revolutionary new high-throughput thermal stability testing instrument specifically designed for biologic drug development.
How to Assess Binding in Drug Discovery
The most popular tool used to characterize binding in the late-discovery phase of drug development is isothermal titration calorimetry (ITC). ITC is a high-resolution method for complete characterization of the basic chemical details of a binding interaction. The calorimeters accomplish this by measuring the heat that is released or absorbed when molecules interact with each other.
How Material Selection Can Make or Break Your PCB Download
eBook How Material Selection Can Make or Break Your PCB Printed circuit boards (PCBs) are the foundation for most of today’s electronic devices. Developers need to bear in mind a variety of considerations, including production standards, material impact on performance, and application conditions. This eBook examines some of the critical issues PCB developers face and…
Using Rheology to Determine the Perfect Viscosity of Gravy
On holiday tables across the world, an unexpected unsung hero can make or break the meal: gravy. The seemingly simple condiment adds a dash of flavor to the star roast, livens up potatoes, and can rescue even the driest turkey that may accidentally make its way to the table.
4 Polymer Insights from Dynamic Mechanical Analysis
From material selection and failure analysis to end-use application, Dynamic Mechanical Analysis (DMA) offers crucial polymer insights. Polymer scientists and design engineers pair DMA with fatigue testing to gain a complete view of their material’s properties and performance attributes.
BioPharma Drug Development Workflow and Techniques
Drug development is a long and complex process that starts with discovery and, if successful, ends with government approval for marketing. Each step in the drug development process, outlined below, has specific goals with the aim of down-selecting appropriate hits and candidates to an approved drug substance.
History of Microcalorimetry
Throughout the 18th century, many scientists questioned the nature of heat. Isaac Newton thought that heat was transferred by the vibrations of particles, while Robert Hooke believed heat was a property of the body that arose from the motion of its parts.