Category Archives: Microcalorimetry Notes

Workflow Solutions: Choosing the Right ITC Binding Experiment

Isothermal titration calorimetry (ITC) is the best technique to obtain a complete understanding of the driving forces leading to a binding interaction. There have been significant advances to the technology and method development leading to a workflow solution for every lab.

A Novel Thermodynamic Assay for Predicting and Monitoring Biomolecular Structure Stability

We performed a comparability study of a liquid protein reference formulation using a nano differential scanning calorimeter (Nano DSC) to reveal that this thermodynamic technology detects the smallest changes in biomolecular structure in response to subtle manipulations in the reference formulation.

Isothermal Microcalorimetry: Pharmaceutical Applications of Microcalorimetry

This application note will review the microcalorimetric techniques that are most commonly used within pharmaceutical science: including stability and compatibility tests, determination of small amounts of amorphic content and characterizing polymorphism.

The Impact of Electrolyte Additives in Lithium-ion Batteries Determined Using Isothermal Microcalorimetry

In this study, a high resolution TAM microcalorimeter equipped with 12 microcalorimeters was used to measure and quantitatively compare the heat flow of lithium-ion batteries that only vary in concentration of electrolyte additive.

An Overview of Isothermal Microcalorimetry in Battery R&D and QA

An overview of isothermal microcalorimetry in battery research, development and quality control in order to illustrate the versatility and providing an idea of the possibilities of isothermal microcalorimetry.