Syringe and needle with glass medical ampoule vials for injection. Medicine is dry white drug penicillin powder or liquid with of aqueous solution in ampulla

Unlocking Stability: The Crucial Role of Thermal Analysis in Lyophilization Temperature Optimization

Microcalorimetry, 生物製藥

The method of drug delivery significantly influences the final stages of the manufacturing process. Currently, lyophilization—a widely adopted technique—enables drug developers to stabilize formulations and therapeutic molecules using a validated commercial approach. In this process, precise control of pressure and temperature within a lyophilizer facilitates the removal of liquids from formulations containing thermally sensitive or hydrolytically unstable active pharmaceutical ingredients or formulation components.

Close up of granulated plastic waste on a recycling plant for pl

Characterization Considerations when Sourcing PCR

Polymers, Thermal Analysis, 流變學

Against the backdrop of a plastic waste crisis, the global demand for plastic is set to quadruple by 2060. This has driven a shift toward sustainability and away from linear use models of plastic production. Post-consumer resin (PCR) has emerged as a key player in circular economy initiatives, though ensuring the quality and performance of PCR requires several characterization considerations.

微量熱法的歷史

Microcalorimetry, 生物製藥

在整個 18 世紀，許多科學家都對熱的本質提出了質疑。艾薩克·牛頓 (Isaac Newton) 認為熱能是透過粒子的震動傳遞的，而勞勃·虎克 (Robert Hooke) 則認為熱能是人體各部位運動而產生的一種特性1。然而，在歷史上第一個眾所周知對熱量進行測量的貢獻者是蘇格蘭醫生和化學家約瑟夫·布拉克 (Joseph Black)1。1761 年，他透過精確的測量發現，對達熔點的冰或達沸點的水施加熱量並不會導致溫度變化1。這個觀察結果使他成為第一個區分溫度和熱量的科學家，標誌了熱力學的開端。

electrode slurries

如何利用流變學改良電池電極漿料

Blog Applications, Blog Techniques, 流變學, 電池與電池材料

從輕薄的筆記型電腦到長途電動汽車，無數應用都需要提高鋰電池的能量密度和性能。由於電池電極直接影響電池的能量密度和性能，因此電池研究人員對電極及其組成特別感興趣，希望將技術推向更高境界。電池漿料加工處理也是製程中的關鍵步驟，是提升效率並降低成本的重大機會。

沙堡的科學

Adhesives & Sealants, Blog Applications, Blog Techniques, 流變學

夏日的藍天與和煦的天氣召喚我們來到海灘嬉戲。畢竟，夏天就是享受陽光、衝浪及沙灘的代名詞。既然來到沙灘，怎麼能不堆沙堡呢？雖然潮起的浪花是所有沙堡建造者的敵人，但浩瀚的大海也是他們最強大的盟友。由於潮濕的沙可以黏在一起，才能如魔法般打造壯觀城堡。乾燥的細沙摸起來很舒服，但無法用來蓋沙堡，絕大部分的原因是內聚力。進行快速測試發現，潮濕和乾燥沙子的內聚力差了十倍！