Rheology Theory and Applications
Will my paint coat the wall or drip off? Will my topical pharmaceutical spread on skin or form clumps? Rheology answers vital questions to inform how we create and interact with materials on a daily basis.
3 Essential Types of Mechanical Testing for Polymer Development
High-performance polymers are a critical material for manufacturers due to their combination of mechanical, thermal, and chemical properties, but especially their cost. Without adequate testing, manufacturers could run into a slew of issues, from immediate product failure to poor performance or failure after some time in usage.
Unlocking Stability: The Crucial Role of Thermal Analysis in Lyophilization Temperature Optimization
The method of drug delivery significantly influences the final stages of the manufacturing process. Currently, lyophilization—a widely adopted technique—enables drug developers to stabilize formulations and therapeutic molecules using a validated commercial approach. In this process, precise control of pressure and temperature within a lyophilizer facilitates the removal of liquids from formulations containing thermally sensitive or hydrolytically unstable active pharmaceutical ingredients or formulation components.
Characterization Considerations when Sourcing PCR
Against the backdrop of a plastic waste crisis, the global demand for plastic is set to quadruple by 2060. This has driven a shift toward sustainability and away from linear use models of plastic production. Post-consumer resin (PCR) has emerged as a key player in circular economy initiatives, though ensuring the quality and performance of PCR requires several characterization considerations.
Thermal Analysis in Pharmaceutical Research, Development, and Quality Control
As a central pillar of modern society, the pharmaceutical industry bears the load of billions of lives around the world. In 2022, the global revenue of the pharmaceutical industry approximated $1.5 trillion, a figure reflected in two decades of significant growth.
Evaluating Battery Slurries with Simultaneous Rheological and Impedance Measurement
Lithium-ion batteries (LIB) are manufactured through a multistep process combining various active and inactive materials. Material selection and processing conditions can greatly affect the final battery performance.
Rheology, Easy as Pie
I love a good experiment in the kitchen, especially when it involves baking and desserts. In celebration of Pi Day, let’s take science and experiments into the kitchen with pie dough and fillings…and a rheometer.
Advance Formulation Performance with Rheology Studies
The progression from formulation development to commercial formulation is dependent on the dose strength, intrinsic stability, and extent of protein self-association in the final drug.1 This is because the drug is reaching the final stage of development.
Applying Dynamic Mechanical Analysis (DMA) to Test the Durability of Protective Sports Equipment
There is a renewed interest in the durability of protective sports equipment after Patrick Mahomes’ helmet recently cracked apart in -4 degrees Fahrenheit (-20 degrees Celsius) weather. Scientists from TA Instruments ran tests to find out if materials found in protective sports equipment can break due to cold weather.
Thermal Analysis for Printed Circuit Boards (PCBs)
Printed circuit boards (PCBs) form the backbone of virtually all electronic applications. Enhancing their performance and reliability is paramount for custom PCB projects, where smaller footprints and improved maintainability lead to enhanced functionality.
How to Assess Binding in Drug Discovery
The most popular tool used to characterize binding in the late-discovery phase of drug development is isothermal titration calorimetry (ITC). ITC is a high-resolution method for complete characterization of the basic chemical details of a binding interaction. The calorimeters accomplish this by measuring the heat that is released or absorbed when molecules interact with each other.
Using Rheology to Determine the Perfect Viscosity of Gravy
On holiday tables across the world, an unexpected unsung hero can make or break the meal: gravy. The seemingly simple condiment adds a dash of flavor to the star roast, livens up potatoes, and can rescue even the driest turkey that may accidentally make its way to the table.