Long Term Stability Analysis of Monoclonal Antibodies

Long Term Stability Analysis of Monoclonal Antibodies Overview Characterization of biopharmaceuticals during all development phases is critical to the candidate selection process and the ongoing production of the active material. Some recent efforts to achieve patient self-administration has required high API concentrations (100-300 mg/mL). Development concerns for the high concentration formulations are denaturation, aggregation and…

Stability Testing of Energetic Materials by Isothermal Microcalorimetry

Stability Testing of Energetic Materials by Isothermal Microcalorimetry Overview This webinar introduces the use of isothermal microcalorimetry for stability measurement of energetic materials. Energetic materials refer to materials, chemicals and substances which exhibit a risk for self-decomposition associated with self-heating ultimately resulting in run-way reactions. Such materials include propellants, percarbonates and peroxides, and these…

Chris Yakacki: Characterization of Active Shape-Memory Polymers

Chris Yakacki: Characterization of Active Shape-Memory Polymers The field of stimuli-sensitive polymers has grown rapidly over the past decade. Actively-moving polymers have gained attention and have been proposed for use in applications from shape-changing biomedical devices to morphing structures. This webinar covers the basics of characterizing shape-memory polymers using thermo-mechanical equipment, such as the Q800 and…

An Introduction To High Pressure Rheology

An Introduction To High Pressure Rheology High pressure rheology explores phenomena that are not accessible at ambient laboratory conditions. Three of the advantages of using a pressure rheometer cell include a controlled environment for volatile fluids, saturating fluids with soluble constituents, and exploring new phase space using a combination of temperature and pressure.

Rubber Process Analyzer (RPA) for Elastomer and Compound Development and Quality Control

Rubber Process Analyzer (RPA) for Elastomer and Compound Development and Quality Control The Rubber Process Analyzer (RPA) is an important tool for developing – and controlling the reliable manufacture of – elastomers and compounds. The RPA can provide far more information than traditional rubber testing methods such as the MDR or Mooney viscometer. In this…

Dile Holton, Ph.D.: Characterization of Drug Binding Activity and Biopharmaceutical Stability

Dile Holton, Ph.D.: Characterization of Drug Binding Activity and Biopharmaceutical Stability This webinar is focused on enthalpy screening, a new and recently published ITC technique that is showing promise for rapidly and accurately characterizing the binding enthalpy of new drugs or biotherapeutics. Rapid and accurate characterization of biopharmaceuticals is essential for the early selection of…

Randy H. Ewoldt: Experimental Challenges of Shear Rheology, How to Avoid Bad Data

Randy H. Ewoldt: Experimental Challenges of Shear Rheology, How to Avoid Bad Data How do you know when to trust your rheology data? How do you avoid bad data? Is there a checklist? Can you co-plot quantitative experimental boundaries against measured data? This presentation will discuss techniques for identifying and minimizing experimental errors and for…

Prof. Mariano Paganelli: Optical Contactless Measurement of Shape- and Dimensional Changes at High Temperature.

Prof. Mariano Paganelli: Optical Contactless Measurement of Shape- and Dimensional Changes at High Temperature. In this webinar, Prof. Paganelli shows how the innovative technologies adopted by TA Instruments’ new Optical Dilatometry Platform (ODP 868) address the requirements of laboratory scientists and manufacturing managers of traditional and advanced ceramics. Additionally, these technologies prove beneficial for power plants…

Norman J. Wagner: An Introduction to Colloidal Suspension Rheology

Norman J. Wagner: An Introduction to Colloidal Suspension Rheology Colloidal suspensions are encountered across a broad range of natural phenomena and industrially relevant products and processes. From coatings and inks, to foods and pharmaceuticals, dispersions, sols, gels, and glasses of colloidal particles exhibit a rich rheological behavior. This webinar will present an introductory overview of…

Kadine Mohomed – Characterization of Amorphous Pharmaceuticals by DSC Analysis

Kadine Mohomed – Characterization of Amorphous Pharmaceuticals by DSC Analysis The glass transition temperature of an amorphous pharmaceutical solid is a critical physical property that can greatly influence the material’s chemical stability, physical stability, and viscoelastic properties. Thankfully with specific analytical tests made possible through the use of Differential Scanning Calorimetry, this and other thermal…