Stability Testing of Energetic Materials by Isothermal Microcalorimetry

Stability Testing of Energetic Materials by Isothermal Microcalorimetry Overview This webinar introduces the use of isothermal microcalorimetry for stability measurement of energetic materials. Energetic materials refer to materials, chemicals and substances which exhibit a risk for self-decomposition associated with self-heating ultimately resulting in run-way reactions. Such materials include propellants, percarbonates and peroxides, and these…

Dile Holton, Ph.D.: Characterization of Drug Binding Activity and Biopharmaceutical Stability

Dile Holton, Ph.D.: Characterization of Drug Binding Activity and Biopharmaceutical Stability This webinar is focused on enthalpy screening, a new and recently published ITC technique that is showing promise for rapidly and accurately characterizing the binding enthalpy of new drugs or biotherapeutics. Rapid and accurate characterization of biopharmaceuticals is essential for the early selection of…

Règles thermodynamiques permettant d’atteindre de fortes affinité et sélectivité de liaison

Une forte affinité et une forte sélectivité sont deux propriétés essentielles des molécules médicamenteuses. Dans la mesure où l’affinité de liaison est déterminée par la somme des contributions enthalpique et entropique, l’obtention de très fortes affinités nécessite l’optimisation de ces deux contributions à la liaison. Une approche efficace nécessite une prédiction précise des contributions des…