Overview An overview of the use of thermal analysis techniques in materials characterization is explored with reference to typical examples of the type, quality, and usefulness of data that can be gathered and the interpretation of results.
Overview Thermogravimetric Analysis, or TGA, is a powerful analytical tool for measuring changes in a sample’s mass as its environmental temperature shifts. When coupled with other instrumental techniques such as mass spectrometers and infrared spectrometers, chemical analysis of the evolved gases is achieved. These hyphenated techniques have a long history in thermal analysis.…
Overview: Antibodies are the most rapidly growing form of therapeutic. High-throughput methods of characterization are essential as companies and researchers move to develop new candidates. In this webinar, Dr. Shawn Owen discusses advanced characterization techniques to assess antibody-drug conjugates (ADCs) and antibody-fusion proteins. For ADCs, the level of payload and site of conjugation are determined…
Benefits of Microscopy for Interpretation of DSC Thermograms DSC thermograms can be complicated and difficult to interpret, sometimes requiring multiple experiments in order to better understand a thermal event. The NEW Microscope Accessory for the Discovery DSC helps to eliminate these issues by allowing the user to easily view the sample while the DSC experiment…
DSC Characterization of Crystalline Structure in Foods and Pharmaceuticals Differential Scanning Calorimetry (DSC) is an analytical technique frequently used to detect and quantify crystalline content of pharmaceuticals, foods, polymers, and many other materials. Appearing as an endothermic peak during heating in a DSC experiment, the temperature and area of the peak can be used to…
Designing New Materials for Additive Manufacturing: Vat Photopolymerization Overview 3D printing, or additive manufacturing (AM), provides opportunities to create previously unattainable geometric objects through layer-by-layer fabrication. Novel macromolecular structures and synthetic methods coupled with unique printing methods lead to 3D part generation with micron-scale resolution and tunable to emerging technologies. By tuning polymer structure, printing…
Kadine Mohomed – Characterization of Amorphous Pharmaceuticals by DSC Analysis The glass transition temperature of an amorphous pharmaceutical solid is a critical physical property that can greatly influence the material’s chemical stability, physical stability, and viscoelastic properties. Thankfully with specific analytical tests made possible through the use of Differential Scanning Calorimetry, this and other thermal…
