Uses of Isothermal Microcalorimetry in Urology In this TA Instruments sponsored webinar, Dr. Olivier Braissant discusses the process of detecting and monitoring biological processes with isothermal calorimetry. This has been shown to be an accurate analytical technique and is proportional to the rate at which a given chemical or physical process takes place.
DetailsOverview In order to meet growing market demands for power storage, Lithium ion and new battery chemistries demand higher energy density, longer cycle life, calendar life, and better safety to a lower cost. Isothermal microcalorimetry is a highly sensitive, non-destructive and non-specific tool to characterize these critical performance criteria. Learn how this method provides:…
DetailsThermodynamic Rules To Achieve High Binding Affinity & Selectivity High affinity and selectivity are two essential properties of drug molecules. Since the binding affinity is determined by the sum of enthalpic and entropic contributions, extremely high affinity necessitates optimization of both contributions to binding. An efficient approach requires accurate prediction of the contributions of specific…
DetailsStability Testing of Energetic Materials by Isothermal Microcalorimetry Overview This webinar introduces the use of isothermal microcalorimetry for stability measurement of energetic materials. Energetic materials refer to materials, chemicals and substances which exhibit a risk for self-decomposition associated with self-heating ultimately resulting in run-way reactions. Such materials include propellants, percarbonates and peroxides, and these…
DetailsPlasma Protein Calorimetry For Clinical Diagnostics In this TA Instruments sponsored webinar, Dr. Nichola Garbett discusses the emerging technique of using high sensitivity DSC analysis of blood plasma for plasma proteome research, and as a clinical diagnostic tool.
DetailsOverview This webinar addresses microcalorimetric testing can shed light on the effects of coatings and sterilization on material stability and how it can support the overall study of the rate, extent, and prevention of cell adhesion.
DetailsMeasuring Thermodynamic Parameters in the Drug Development Process Is there a benefit to measuring thermodynamic parameters in the drug development process? In this TA Instruments Webinar, Dr. John E. Ladbury discusses Thermodynamic Parameterization of protein-ligand interaction, not only provides quantification of the affinity of an interaction, but also the underlying changes in enthalpy and entropy.…
DetailsLong Term Stability Analysis of Monoclonal Antibodies Overview Characterization of biopharmaceuticals during all development phases is critical to the candidate selection process and the ongoing production of the active material. Some recent efforts to achieve patient self-administration has required high API concentrations (100-300 mg/mL). Development concerns for the high concentration formulations are denaturation, aggregation…
DetailsIsothermal Microcalorimetry in Pharmaceutical Science This webinar will review the microcalorimetric techniques that are most commonly used within pharmaceutical science, including stability and compatibility tests, determination of small amounts of amorphic content, and characterizing polymorphism. A microcalorimeter can quantify the amount and rate of heat release from chemical processes associated with stability and shelf…
DetailsWebinar Introducing the RS-DSC: A Dilution-Free Method for Screening Thermal Stability of High Concentration Biotherapeutics Ensuring short-term thermal stability is essential for maintaining the quality and achieving regulatory approval of antibody drug products. The TA Instruments™ RS-DSC (Rapid Screening-Differential Scanning Calorimeter) offers an advanced platform for thermal stability screening of buffer formulations and protein sequence…
DetailsIntroducing the new TAM IV & TAM IV-48 Microcalorimeters The new TAM IV is the world’s most sensitive, stable, and flexible microcalorimeter system. It is completely modular and combines the highest heat flow sensitivity with unmatched long-term temperature stability to measure processes that are undetectable by other techniques.
DetailsIntroducing the New TAM Air Isothermal Calorimeter This webinar introduces the all-new TAM Air Isothermal Calorimeter. Delivering the performance, reliability, and ease-of-use that is the hallmark of TA Instruments products, the new TAM Air maintains its leadership position as the instrument of choice for cement and concrete hydration analysis using ASTM C1702 and C1679, as…
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