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Oct182017

Stability Testing of Energetic Materials by Isothermal Microcalorimetry

Microcalorimetry, Videos, Webinars

Stability Testing of Energetic Materials by Isothermal Microcalorimetry Overview This webinar introduces the use of isothermal microcalorimetry for stability measurement of energetic materials. Energetic materials refer to materials, chemicals and substances which exhibit a risk for self-decomposition associated with self-heating ultimately resulting in run-way reactions. Such materials include propellants, percarbonates and peroxides, and these…

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Mar152017

Introducing the New TAM Air Isothermal Calorimeter

Microcalorimetry, Webinars

Introducing the New TAM Air Isothermal Calorimeter This webinar introduces the all-new TAM Air Isothermal Calorimeter. Delivering the performance, reliability, and ease-of-use that is the hallmark of TA Instruments products, the new TAM Air maintains its leadership position as the instrument of choice for cement and concrete hydration analysis using ASTM C1702 and C1679, as…

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Oct202016

Dile Holton, Ph.D.: Characterization of Drug Binding Activity and Biopharmaceutical Stability

Microcalorimetry, Videos, Webinars

Dile Holton, Ph.D.: Characterization of Drug Binding Activity and Biopharmaceutical Stability This webinar is focused on enthalpy screening, a new and recently published ITC technique that is showing promise for rapidly and accurately characterizing the binding enthalpy of new drugs or biotherapeutics. Rapid and accurate characterization of biopharmaceuticals is essential for the early selection of…

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Mar32016

In Search of Calorimetric Answers to Events In Self Assemblies

Microcalorimetry, Webinars

In Search of Calorimetric Answers to Events In Self Assemblies In this TA Webinar, Professor Nand Kishore discusses how to best discover and interpret protein folding, ligand binding, aggregation and molecular partitioning in self assemblies. Isothermal titration (ITC) and differential scanning calorimetry (DSC) are powerful tools for thermodynamic characterization of protein folding intermediates, drug-protein…

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Aug132015

Measuring Thermodynamic Parameters in the Drug Development Process

Microcalorimetry, Webinars

Measuring Thermodynamic Parameters in the Drug Development Process Is there a benefit to measuring thermodynamic parameters in the drug development process? In this TA Instruments Webinar, Dr. John E. Ladbury discusses Thermodynamic Parameterization of protein-ligand interaction, not only provides quantification of the affinity of an interaction, but also the underlying changes in enthalpy and entropy.…

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Aug132015

Thermodynamic Rules To Achieve High Binding Affinity & Selectivity

Microcalorimetry, Webinars

Thermodynamic Rules To Achieve High Binding Affinity & Selectivity High affinity and selectivity are two essential properties of drug molecules. Since the binding affinity is determined by the sum of enthalpic and entropic contributions, extremely high affinity necessitates optimization of both contributions to binding. An efficient approach requires accurate prediction of the contributions of specific…

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