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How to Assess Binding in Drug Discovery

The most popular tool used to characterize binding in the late-discovery phase of drug development is isothermal titration calorimetry (ITC). ITC is a high-resolution method for complete characterization of the basic chemical details of a binding interaction. The calorimeters accomplish this by measuring the heat that is released or absorbed when molecules interact with each other.

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How to Optimize Battery Electrode Slurries with Rheology

From lightweight laptops to cross-country EV driving, countless applications require increasing lithium-ion batteries’ energy density and performance. Since battery electrodes directly contribute to these aspects of battery function, electrodes and their components are of particular interest to battery researchers seeking to advance technology to the next level. Battery slurry processing is also a key step of manufacturing, offering significant opportunities to increase efficiency while reducing cost.

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The Science of Sandcastles

Summer’s blue skies and warm temperatures beckon us to the beach. After all, summer is synonymous with fun in the sun, surf, and sand. And what is a day in the sand without building a sandcastle? While rising tides can be every sandcastle builder’s enemy, the ocean is also their greatest ally. That’s because damp sand sticks together, allowing sandcastle magic. Dry, powdery sand may feel nice but it’s no friend of castle building and a large part of that is down to cohesion. Quick tests of moist and dry sand showed a 10x difference in cohesion!

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Powder Rheology for Pharmaceutical Development

Pharmaceutical development is highly regulated, and for good reason. Potential new products must be rigorously tested to ensure their safety, purity, and performance are acceptable before coming to market. For topical creams, regulations uphold stability lifetime parameters and require identification of any impurities before products reach consumers.

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Lithium-ion Battery Quality and Performance Testing with Isothermal Microcalorimetry

Over the past decade, battery research, development, and quality control have adopted in-situ and in-operando isothermal microcalorimetry (IMC) as the leading method to evaluate heat flow during lithium-ion battery cycling. While cycling a cell to failure can take many months, emerging diagnostic tests are able to predict long-term behavior in a matter of weeks.

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