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Aug192024

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Why DSC Testing is a Critical Step in Developing Biosimilar Drugs

Biopharmaceuticals, Microcalorimetry

Biologic therapies derived from living organisms have revolutionized the treatment of complex diseases, yet their high development costs are often passed onto patients. Biosimilar drugs offer a promising solution to reduce costs while maintaining therapeutic efficacy. Unlike generic drugs, biosimilars cannot be exact replicas of their reference biologics due to their complex structures, necessitating rigorous testing and regulatory approval.

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Jul292024

Composites Industry Blog

Overcoming Composites R&D Challenges with Material Analysis

Composites, Mechanical Testing, Rheology, Thermal Analysis

The composites market is evolving fast. Global market projections indicate a 10.8 % growth by 2028, driven by the demand for composites across industries looking for materials with superior performance at reduced weight and cost. This blog explores how advanced material analysis can enhance R&D and manufacturing processes in the composites market, ultimately leading to financial savings and increased efficiency.

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Jul232024

Chip filling

How to Accelerate Thermal Stability Testing for High-Concentration Drugs

Biopharmaceuticals, Microcalorimetry

The stability of high-concentration drugs can change under storage conditions, but until now, thermal testing in the lab using traditional calorimetry methods has been time-consuming and challenging. The new TA Instruments RS-DSC fills a critical antibody formulation development gap by allowing for high-throughput short-term thermal stability testing at formulation strength concentrations. In this blog, we explore why that’s essential.

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May282024

Syringe and needle with glass medical ampoule vials for injection. Medicine is dry white drug penicillin powder or liquid with of aqueous solution in ampulla

Unlocking Stability: The Crucial Role of Thermal Analysis in Lyophilization Temperature Optimization

Biopharmaceuticals, Microcalorimetry

The method of drug delivery significantly influences the final stages of the manufacturing process. Currently, lyophilization—a widely adopted technique—enables drug developers to stabilize formulations and therapeutic molecules using a validated commercial approach. In this process, precise control of pressure and temperature within a lyophilizer facilitates the removal of liquids from formulations containing thermally sensitive or hydrolytically unstable active pharmaceutical ingredients or formulation components.

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May132024

Close up of granulated plastic waste on a recycling plant for pl

Characterization Considerations when Sourcing PCR

Polymers, Rheology, Thermal Analysis

Against the backdrop of a plastic waste crisis, the global demand for plastic is set to quadruple by 2060. This has driven a shift toward sustainability and away from linear use models of plastic production. Post-consumer resin (PCR) has emerged as a key player in circular economy initiatives, though ensuring the quality and performance of PCR requires several characterization considerations.

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