In this note, the processing behavior of two lactose excipients is studied by measuring shear and flowability of milled and spray-dried lactose. Milled lactose was found to have higher cohesion, yield strength, confined and unconfined flow energies when compared to spray-dried lactose.
DetailsThe TA Instruments Powder Rheology Accessory was used with Discovery HR 30 rheometer to perform shear measurements. Duplicate measurements were performed with fresh samples under ambient conditions.
DetailsPharmaceutical development is highly regulated, and for good reason. Potential new products must be rigorously tested to ensure their safety, purity, and performance are acceptable before coming to market. For topical creams, regulations uphold stability lifetime parameters and require identification of any impurities before products reach consumers.
DetailsDescription The Powder Rheology Accessory expands the DHR’s capabilities to powders, enabling characterization of behaviors during storage, dispensing, processing and end use. Product development and process optimization are accelerated with quantitative measurements of dynamic flowability and shear properties of consolidated powder. Screening new formulations or incoming raw materials detects unexpected behavior to avoid large-scale…
DetailsPowder Rheology Description Features & Benefits Technology Applications Videos Resources The Powder Rheology Accessory expands the DHR’s capabilities to powders, enabling characterization of behaviors during storage, dispensing, processing and end use. Product development and process optimization are accelerated with quantitative measurements of dynamic flowability and shear properties of consolidated powder, under ambient conditions or controlled…
DetailsOverview In this Tech Tip, we will set up the TA Instruments powder rheology flow cell.
DetailsFrom fresh steak to new phones, the goods we buy are usually wrapped in one thing: plastic. And plastic dominates how we pack and store products for good reason – it is lightweight, cost-efficient, and durable. Plastic helps us transport and receive goods in perfect condition, thus reducing food waste and preventing damaged goods from heading to landfills.
DetailsOverview The polymer used in a compound recipe is critical to compound processing behavior and final product performance, yet polymer characterization is an under-utilized technique in the rubber industry. Traditionally, the rheological behavior of the raw polymer is characterized using Mooney viscosity, which provides limited information. The Rubber Process Analyzer (RPA) can better characterize…
DetailsThe auto-trim accessory for Discovery Hybrid Rheometers automates the melting, gap setting, and crucial sample trimming step in polymer melt rheology testing. The automation of this step improves data consistency by up to 5x, increases continuous walkaway time by 80%, and reduces new operator training time to less than 30 minutes.
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