Microcalorimetric Testing of Biomedical Devices Medical Devices Webinar Series | 5 of 6 This webinar addresses microcalorimetric testing can shed light on the effects of coatings and sterilization on material stability and how it can support the overall study of the rate, extent, and prevention of cell adhesion. Episode #1 – Chemical Characterization of Medical…
DetailsMaterial characterization for medical devices Watch our on-demand medical devices testing webinar series to gain expert insight into the critical factors involved in medical device design, testing, and regulatory compliance – including mechanical, fatigue, and durability testing and the rheological study of soft biomaterials.
DetailsOverview This presentation will introduce a range of biomaterials test applications where mechanical test instruments are assisting researchers and engineers in gaining a better understanding of native and artificial tissues. Tissue characterization often leverages test techniques designed to measure quasi-static and dynamic properties of human or animal model tissues. These measurements can be used to…
DetailsOverview Fatigue and durability testing are critical applications in the regulatory submission process. A variety of methods are discussed in helping to develop predictions for the design, optimization, and approval of medical devices.
DetailsMeasuring Thermodynamic Parameters in the Drug Development Process Is there a benefit to measuring thermodynamic parameters in the drug development process? In this TA Instruments Webinar, Dr. John E. Ladbury discusses Thermodynamic Parameterization of protein-ligand interaction, not only provides quantification of the affinity of an interaction, but also the underlying changes in enthalpy and entropy.…
DetailsOverview The impact of humidity on a material’s properties and performance during processing, storage, and in final form is a growing area of interest for manufacturers across many industries. A few areas of investigation of this impact include material selection and failure analysis of layered materials used with electronic circuit boards, morphological changes in…
DetailsLong Term Stability Analysis of Monoclonal Antibodies Overview Characterization of biopharmaceuticals during all development phases is critical to the candidate selection process and the ongoing production of the active material. Some recent efforts to achieve patient self-administration has required high API concentrations (100-300 mg/mL). Development concerns for the high concentration formulations are denaturation, aggregation…
DetailsKadine Mohomed – Characterization of Amorphous Pharmaceuticals by DSC Analysis The glass transition temperature of an amorphous pharmaceutical solid is a critical physical property that can greatly influence the material’s chemical stability, physical stability, and viscoelastic properties. Thankfully with specific analytical tests made possible through the use of Differential Scanning Calorimetry, this and other thermal…
DetailsJan Vermant – Orthogonal Superposition Rheology OVERVIEW Superposition flows in rheology are powerful methods to understand non-linear and anisotropic viscoelasticity. Parallel Superposition experiments have been historically simple to perform, but are difficult to understand and do not provide all of the desired information. Recent developments have made Orthogonal Superposition more simple to perform, allowing…
DetailsIsothermal Microcalorimetry in Pharmaceutical Science This webinar will review the microcalorimetric techniques that are most commonly used within pharmaceutical science, including stability and compatibility tests, determination of small amounts of amorphic content, and characterizing polymorphism. A microcalorimeter can quantify the amount and rate of heat release from chemical processes associated with stability and shelf…
DetailsWebinar Introducing the RS-DSC: A Dilution-Free Method for Screening Thermal Stability of High Concentration Biotherapeutics Ensuring short-term thermal stability is essential for maintaining the quality and achieving regulatory approval of antibody drug products. The TA Instruments™ RS-DSC (Rapid Screening-Differential Scanning Calorimeter) offers an advanced platform for thermal stability screening of buffer formulations and protein sequence…
DetailsIntroducing the new TAM IV & TAM IV-48 Microcalorimeters The new TAM IV is the world’s most sensitive, stable, and flexible microcalorimeter system. It is completely modular and combines the highest heat flow sensitivity with unmatched long-term temperature stability to measure processes that are undetectable by other techniques.
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