The progression from formulation development to commercial formulation is dependent on the dose strength, intrinsic stability, and extent of protein self-association in the final drug.1 This is because the drug is reaching the final stage of development.
DetailsThe RS-DSC is for preclinical development of antibodies, antibody-drug conjugates, and vaccines where dosage forms are typically greater than 50 µg.
DetailsAdditional Resources For further information, please see the corresponding app note, An Overview of Isothermal Microcalorimetry in Battery R&D and QA.
DetailsCandidate selection is the third phase of the drug development process. The main purpose of candidate selection is to continue screening and filtering down to the most promising antibodies, ideally having one or two progress forward. During this phase, researchers are looking to evaluate the developability of a pool of less than five antibodies.
DetailsThere is a renewed interest in the durability of protective sports equipment after Patrick Mahomes’ helmet recently cracked apart in -4 degrees Fahrenheit (-20 degrees Celsius) weather. Scientists from TA Instruments ran tests to find out if materials found in protective sports equipment can break due to cold weather.
DetailsThe Battery Cycler Microcalorimeter solution is an end-to-end, in-operando measurement tool for elucidating the thermodynamic and electrochemical details of battery cells in real time, in a flexible and intuitive system.
DetailsPrinted circuit boards (PCBs) form the backbone of virtually all electronic applications. Enhancing their performance and reliability is paramount for custom PCB projects, where smaller footprints and improved maintainability lead to enhanced functionality.
DetailsThe TA RS-DSC is a revolutionary new high-throughput thermal stability testing instrument specifically designed for biologic drug development.
DetailsThe most popular tool used to characterize binding in the late-discovery phase of drug development is isothermal titration calorimetry (ITC). ITC is a high-resolution method for complete characterization of the basic chemical details of a binding interaction. The calorimeters accomplish this by measuring the heat that is released or absorbed when molecules interact with each other.
DetailseBook How Material Selection Can Make or Break Your PCB Printed circuit boards (PCBs) are the foundation for most of today’s electronic devices. Developers need to bear in mind a variety of considerations, including production standards, material impact on performance, and application conditions. This eBook examines some of the critical issues PCB developers face and…
DetailsOn holiday tables across the world, an unexpected unsung hero can make or break the meal: gravy. The seemingly simple condiment adds a dash of flavor to the star roast, livens up potatoes, and can rescue even the driest turkey that may accidentally make its way to the table.
DetailsFrom material selection and failure analysis to end-use application, Dynamic Mechanical Analysis (DMA) offers crucial polymer insights. Polymer scientists and design engineers pair DMA with fatigue testing to gain a complete view of their material’s properties and performance attributes.
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