The most popular tool used to characterize binding in the late-discovery phase of drug development is isothermal titration calorimetry (ITC). ITC is a high-resolution method for complete characterization of the basic chemical details of a binding interaction. The calorimeters accomplish this by measuring the heat that is released or absorbed when molecules interact with each other.
DetailsOverview Whether you’re new to Dynamic Mechanical Analysis or simply want to explore new accessories and testing procedures, our help guides are a valuable resource. These guides come pre-installed on your DMA 850 to help you get started. Discover tips on using different geometries, training new users, setting up experiments, analyzing data, and more. Find…
DetailsThe stability of high-concentration drugs can change under storage conditions, but until now, thermal testing in the lab using traditional calorimetry methods has been time-consuming and challenging. The new TA Instruments RS-DSC fills a critical antibody formulation development gap by allowing for high-throughput short-term thermal stability testing at formulation strength concentrations. In this blog, we explore why that’s essential.
DetailsRheology is a notoriously complex field, combining mathematics and physics to characterize materials. For inexperienced users, rheology can seem like a massive challenge. Luckily, new technology simplifies rheology down to its core so you can get essential measurements without difficult training, measurements, or calculations.
DetailsDynamic mechanical analysis (DMA) is a technique to measure the response of materials when they are subjected to dynamic or cyclic forces. Typically, dynamic mechanical analysis involves looking at the elastic and viscous response of the material when it is under a small oscillating load that probes the molecular structure’s response to the perturbation . Other variables, such as temperature, time and frequency may be changed as part of the testing to characterize how the material performs under different environmental conditions.
DetailseBook How Material Selection Can Make or Break Your PCB Printed circuit boards (PCBs) are the foundation for most of today’s electronic devices. Developers need to bear in mind a variety of considerations, including production standards, material impact on performance, and application conditions. This eBook examines some of the critical issues PCB developers face and…
DetailsResult of over twenty years of R&D of optical instruments for the study of the thermo-mechanical behavior of materials, HM 867 makes possible the analysis of samples beyond the limits of classical heating microscopy. Its versatility makes of HM 867 the most innovative tool for both R&D and for the optimization of all the industrial processes that involve thermal cycles.
Adopting state-of-the-art technologies in the field of optical and thermal analysis, it is supplied with Misura 4 Thermal Analysis software, the proven software platform that provides an intuitive interface for instrument control and data handling and features the most thorough and precise image analysis.
DetailsThroughout the 18th century, many scientists questioned the nature of heat. Isaac Newton thought that heat was transferred by the vibrations of particles, while Robert Hooke believed heat was a property of the body that arose from the motion of its parts.
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